I smoke Virginia (flake) >90% of the time and once I'm familiar with and like a tobacco I tend to rotate them in my venerated smooth smokers without too much internal debate, so they're basically dedicated to these types of tobaccos.
Virginia with higher acid levels or non-Virginias (latakia) I smoke in sandblasts or rusticated and I do differentiate based on how the pipe smokes.
Pipes that I'm auditioning tend to get a wider variety of tobacco based on their shape, finish and size. I have made the mistake of trying some poor tobaccos in some of my front line pipes and neither of us appreciated it.
I know that some folks like to smoke specific tobaccos in specific pipes. I've found that not to be necessary as long as the mixture is of the same type, meaning that a VA/Lat flake isn't the same as a 100% VA flake. I smoke any Gawith (Sam or Hoggarth) in the same pipes but never Lancer's Slices.